FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SLUG
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
30kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human SLUG expressed in E. Coli.
特异性
SLUG Monoclonal Antibody detects endogenous levels of SLUG protein.
基因名称
SNAI2
蛋白名称
Zinc finger protein SNAI2
别名
SNAI2;SLUG;SLUGH;Zinc finger protein SNAI2;Neural crest transcription factor Slug;Protein snail homolog 2
Organism-1
Human
基因ID-1
6591
SwissProt-1
O43623
Organism-2
Mouse
SwissProt-2
P97469
背景
snail family transcriptional repressor 2(SNAI2) Homo sapiens This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm. Observed in discrete foci in interphase nuclei. These nuclear foci do not overlap with the nucleoli, the SP100 and the HP1 heterochromatin or the coiled body, suggesting SNAI2 is associated with active transcription or active splicing regions.
