FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
S100B
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
11kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of S-100 β expressed in E. Coli.
特异性
S-100 β Monoclonal Antibody detects endogenous levels of S-100 β protein.
基因名称
S100B
蛋白名称
Protein S100-B
别名
S100B;Protein S100-B;S-100 protein beta chain;S-100 protein subunit beta;S100 calcium-binding protein B
Organism-1
Human
基因ID-1
6285
SwissProt-1
P04271
Organism-2
Mouse
SwissProt-2
P50114
背景
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy
细胞定位
Cytoplasm . Nucleus .
