FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Rtn-3
反应性
Human
应用
IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
推荐稀释比
IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of Rtn-3 expressed in E. Coli.
特异性
Rtn-3 Monoclonal Antibody detects endogenous levels of Rtn-3 protein.
基因名称
RTN3
蛋白名称
Reticulon-3
别名
RTN3;ASYIP;NSPL2;Reticulon-3;Neuroendocrine-specific protein-like 2;NSP-like protein 2;Neuroendocrine-specific protein-like II;NSP-like protein II;NSPLII
Organism-1
Human
基因ID-1
10313
SwissProt-1
O95197
Organism-2
Mouse
SwissProt-2
Q9ES97
背景
This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, and pseudogenes of this gene are located on chromosomes 4 and 12. [provided by RefSeq, May 2012],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .
