FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
R-Spondin
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
29kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of R-spondin1 expressed in E. Coli.
特异性
R-Spondin Monoclonal Antibody detects endogenous levels of R-Spondin protein.
基因名称
RSPO1
蛋白名称
R-spondin-1
别名
RSPO1;R-spondin-1;Roof plate-specific spondin-1;hRspo1
Organism-1
Human
基因ID-1
284654
SwissProt-1
Q2MKA7
Organism-2
Mouse
SwissProt-2
Q9Z132
背景
This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014],
细胞定位
Secreted . Nucleus . Seems to mainly localize to nucleoli. .
