FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Rab 10
反应性
Human,Mouse
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
23kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Rab 10 expressed in E. Coli.
特异性
Rab 10 Monoclonal Antibody detects endogenous levels of Rab 10 protein.
基因名称
RAB10
蛋白名称
Ras-related protein Rab-10
别名
RAB10;Ras-related protein Rab-10
Organism-1
Human
基因ID-1
10890
SwissProt-1
P61026
Organism-2
Mouse
基因ID-2
19325
SwissProt-2
P61027
背景
RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009],
细胞定位
Cytoplasmic vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Golgi apparatus membrane . Golgi apparatus, trans-Golgi network membrane . Endosome membrane . Recycling endosome membrane . Cytoplasmic vesicle, phagosome membrane . Cytoplasm, cytoskeleton, cilium basal body . Endoplasmic reticulum membrane . Cytoplasm, perinuclear region . Associates with SLC2A4/GLUT4 storage vesicles (PubMed:22908308). Localizes to the base of the cilium when phosphorylated by LRRK2 on Thr-73 (PubMed:20576682, PubMed:30398148). Transiently associates with phagosomes (By similarity). Localizes to the endoplasmic reticulum at domains of new tubule growth (PubMed:23263280). .
