FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PTH/PTHrP-R
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
66kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human PTH/PTHrP-R expressed in E. Coli.
特异性
PTH/PTHrP-R Monoclonal Antibody detects endogenous levels of PTH/PTHrP-R protein.
基因名称
PTH1R
蛋白名称
Parathyroid hormone/parathyroid hormone-related peptide receptor
别名
PTH1R;PTHR;PTHR1;Parathyroid hormone/parathyroid hormone-related peptide receptor;PTH/PTHrP type I receptor;PTH/PTHr receptor;Parathyroid hormone 1 receptor;PTH1 receptor
Organism-1
Human
基因ID-1
5745
SwissProt-1
Q03431
Organism-2
Mouse
SwissProt-2
P41593
背景
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010],
细胞定位
Cell membrane ; Multi-pass membrane protein .
