- 产品信息
商品描述
靶点-Target
Protein Z
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
45kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of Protein Z expressed in E. Coli.
特异性
Protein Z Monoclonal Antibody detects endogenous levels of Protein Z protein.
基因名称
PROZ
蛋白名称
Vitamin K-dependent protein Z
别名
PROZ;Vitamin K-dependent protein Z
Organism-1
Human
基因ID-1
8858
SwissProt-1
P22891
Organism-2
Mouse
SwissProt-2
Q9CQW3
背景
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012],
细胞定位
Secreted.





