- 产品信息
商品描述
靶点-Target
CARM1
反应性
Human,Rat,Monkey
应用
WB,IHC,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
66kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human PRMT4 expressed in E. Coli.
特异性
PRMT4 Monoclonal Antibody detects endogenous levels of PRMT4 protein.
基因名称
CARM1
蛋白名称
Histone-arginine methyltransferase CARM1
别名
CARM1;PRMT4;Histone-arginine methyltransferase CARM1;Coactivator-associated arginine methyltransferase 1;Protein arginine N-methyltransferase 4
Organism-1
Human
基因ID-1
10498
SwissProt-1
Q86X55
Organism-2
Mouse
SwissProt-2
Q9WVG6
Organism-3
Rat
基因ID-3
363026
SwissProt-3
Q4AE70
背景
This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9. [provided by RefSeq, Aug 2013],
细胞定位
Nucleus . Cytoplasm . Mainly nuclear during the G1, S and G2 phases of the cell cycle (PubMed:19843527). Cytoplasmic during mitosis, after breakup of the nuclear membrane (PubMed:19843527). .





