- 产品信息
商品描述
靶点-Target
PMR1
反应性
Human,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
101kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of PMR1 expressed in E. Coli.
特异性
PMR1 Monoclonal Antibody detects endogenous levels of PMR1 protein.
基因名称
ATP2C1
蛋白名称
Calcium-transporting ATPase type 2C member 1
别名
ATP2C1;KIAA1347;PMR1L;HUSSY-28;Calcium-transporting ATPase type 2C member 1;ATPase 2C1;ATP-dependent Ca;2+;pump PMR1
Organism-1
Human
基因ID-1
27032
SwissProt-1
P98194
Organism-2
Mouse
SwissProt-2
Q80XR2
背景
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium ions. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],
细胞定位
Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein . Golgi apparatus, Golgi stack membrane ; Multi-pass membrane protein . During neuron differentiation, shifts from juxtanuclear Golgi position to multiple Golgi structures distributed over the neural soma with a predominance in the apical dendritic trunk. .





