FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Pinch-1
反应性
Human
应用
WB,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
37kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Pinch-1 expressed in E. Coli.
特异性
Pinch-1 Monoclonal Antibody detects endogenous levels of Pinch-1 protein.
基因名称
LIMS1
蛋白名称
LIM and senescent cell antigen-like-containing domain protein 1
别名
LIMS1;PINCH;PINCH1;LIM and senescent cell antigen-like-containing domain protein 1;Particularly interesting new Cys-His protein 1;PINCH-1;Renal carcinoma antigen NY-REN-48
Organism-1
Human
基因ID-1
3987
SwissProt-1
P48059
Organism-2
Mouse
SwissProt-2
Q99JW4
背景
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010],
细胞定位
Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
