FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PDK1
反应性
Human,Rat,Monkey
应用
WB,IHC,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
49kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human PDK1 expressed in E. Coli.
特异性
PDK1 Monoclonal Antibody detects endogenous levels of PDK1 protein.
基因名称
PDK1
蛋白名称
[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1 mitochondrial
别名
PDK1;PDHK1;[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1;mitochondrial;Pyruvate dehydrogenase kinase isoform 1
Organism-1
Human
基因ID-1
5163
SwissProt-1
Q15118
Organism-2
Mouse
SwissProt-2
Q8BFP9
Organism-3
Rat
SwissProt-3
Q63065
背景
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013],
细胞定位
Mitochondrion matrix .
