- 产品信息
商品描述
靶点-Target
PBEF
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
56kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of PBEF expressed in E. Coli.
特异性
PBEF Monoclonal Antibody detects endogenous levels of PBEF protein.
基因名称
NAMPT
蛋白名称
Nicotinamide phosphoribosyltransferase
别名
NAMPT;PBEF;PBEF1;Nicotinamide phosphoribosyltransferase;NAmPRTase;Nampt;Pre-B-cell colony-enhancing factor 1;Pre-B cell-enhancing factor;Visfatin
Organism-1
Human
基因ID-1
10135
SwissProt-1
P43490
Organism-2
Mouse
SwissProt-2
Q99KQ4
背景
This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10. [provided by RefSeq, Feb 2011],
细胞定位
Nucleus . Cytoplasm . Secreted . Under non-inflammatory conditions, visfatin predominantly exhibits a granular pattern within the nucleus. Secreted by endothelial cells upon IL-1beta stimulation. Abundantly secreted in milk, reaching 100-fold higher concentrations compared to maternal serum. .





