- 产品信息
商品描述
靶点-Target
Pax-6
反应性
Human
应用
WB,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
47kD
推荐稀释比
WB 1:500-1:2000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Pax-6 expressed in E. Coli.
特异性
Pax-6 Monoclonal Antibody detects endogenous levels of Pax-6 protein.
基因名称
PAX6
蛋白名称
Paired box protein Pax-6
别名
PAX6;AN2;Paired box protein Pax-6;Aniridia type II protein;Oculorhombin
Organism-1
Human
基因ID-1
5080
SwissProt-1
P26367
Organism-2
Mouse
SwissProt-2
P63015
背景
This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015],
细胞定位
Nucleus .; [Isoform 1]: Nucleus .; [Isoform 5a]: Nucleus .





