FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PARL
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
42kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.
特异性
PARL Monoclonal Antibody detects endogenous levels of PARL protein.
基因名称
PARL
蛋白名称
Presenilins-associated rhomboid-like protein mitochondrial
别名
PARL;PSARL;Presenilins-associated rhomboid-like protein;mitochondrial;Mitochondrial intramembrane cleaving protease PARL
Organism-1
Human
基因ID-1
55486
SwissProt-1
Q9H300
Organism-2
Mouse
SwissProt-2
Q5XJY4
背景
This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease. [provided by RefSeq, May 2016],
细胞定位
Mitochondrion inner membrane ; Multi-pass membrane protein .; [P-beta]: Nucleus . Translocated into the nucleus by an unknown mechanism (PubMed:17116872). .
