FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PAR4
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
37kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of PAR4 (aa1-330) expressed in E. Coli.
特异性
PAR4 Monoclonal Antibody detects endogenous levels of PAR4 protein.
基因名称
PAWR
蛋白名称
PRKC apoptosis WT1 regulator protein
别名
PAWR;PAR4;PRKC apoptosis WT1 regulator protein;Prostate apoptosis response 4 protein;Par-4
Organism-1
Human
基因ID-1
5074
SwissProt-1
Q96IZ0
Organism-2
Mouse
SwissProt-2
Q925B0
背景
The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Nucleus. Mainly cytoplasmic in absence of apoptosis signal and in normal cells. Nuclear in most cancer cell lines. Nuclear entry seems to be essential but not sufficient for apoptosis (By similarity). Nuclear localization includes nucleoplasm and PML nuclear bodies. .
