FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
p40/p63
反应性
Human,Mouse,Rat,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
77kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Synthesized peptide of human p63.
特异性
p63 Monoclonal Antibody detects endogenous levels of p63 protein.
基因名称
TP63
蛋白名称
Tumor protein 63
别名
TP63;KET;P63;P73H;P73L;TP73L;Tumor protein 63;p63;Chronic ulcerative stomatitis protein;CUSP;Keratinocyte transcription factor KET;Transformation-related protein 63;TP63;Tumor protein p73-like;p73L;p40;p51
Organism-1
Human
基因ID-1
8626
SwissProt-1
Q9H3D4
Organism-2
Mouse
基因ID-2
22061
SwissProt-2
O88898
Organism-3
Rat
基因ID-3
246334
SwissProt-3
Q9JJP6
背景
tumor protein p63(TP63) Homo sapiens This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain, a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance, adult stem/progenitor cell regulation, heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrim
细胞定位
Nucleus .
