FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
OTX2
反应性
Human
应用
WB,IHC,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
32kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human OTX2 expressed in E. Coli.
特异性
OTX2 Monoclonal Antibody detects endogenous levels of OTX2 protein.
基因名称
OTX2
蛋白名称
Homeobox protein OTX2
别名
OTX2;Homeobox protein OTX2;Orthodenticle homolog 2
Organism-1
Human
基因ID-1
5015
SwissProt-1
P32243
Organism-2
Mouse
SwissProt-2
P80206
背景
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012],
细胞定位
Nucleus .
