FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
OPG
反应性
Human
应用
WB,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
46kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human OPG expressed in E. Coli.
特异性
OPG Monoclonal Antibody detects endogenous levels of OPG protein.
基因名称
TNFRSF11B
蛋白名称
Tumor necrosis factor receptor superfamily member 11B
别名
TNFRSF11B;OCIF;OPG;Tumor necrosis factor receptor superfamily member 11B;Osteoclastogenesis inhibitory factor;Osteoprotegerin
Organism-1
Human
基因ID-1
4982
SwissProt-1
O00300
Organism-2
Mouse
SwissProt-2
O08712
背景
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Secreted.
