FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NOS3/eNOS
反应性
Human
应用
IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
130-140kD
推荐稀释比
IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human NOS3 expressed in E. Coli.
特异性
NOS3 Monoclonal Antibody detects endogenous levels of NOS3 protein.
基因名称
NOS3
蛋白名称
Nitric oxide synthase, endothelial
别名
NOS3;Nitric oxide synthase;endothelial;Constitutive NOS;cNOS;EC-NOS;Endothelial NOS;eNOS;NOS type III;NOSIII
Organism-1
Human
基因ID-1
4846
SwissProt-1
P29474
Organism-2
Mouse
SwissProt-2
P70313
背景
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],
细胞定位
Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.
