- 产品信息
商品描述
靶点-Target
Nkx-2.5
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
35kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Nkx-2.5 expressed in E. Coli.
特异性
Nkx-2.5 Monoclonal Antibody detects endogenous levels of Nkx-2.5 protein.
基因名称
NKX2-5
蛋白名称
Homeobox protein Nkx-2.5
别名
NKX2-5;CSX;NKX2.5;NKX2E;Homeobox protein Nkx-2.5;Cardiac-specific homeobox;Homeobox protein CSX;Homeobox protein NK-2 homolog E
Organism-1
Human
基因ID-1
1482
SwissProt-1
P52952
Organism-2
Mouse
SwissProt-2
P42582
背景
This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
细胞定位
Nucleus .





