FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NCOR1
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
270kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of N-CoR (aa1-192) expressed in E. Coli.
特异性
N-CoR Monoclonal Antibody detects endogenous levels of N-CoR protein.
基因名称
NCOR1
蛋白名称
Nuclear receptor corepressor 1
别名
NCOR1;KIAA1047;Nuclear receptor corepressor 1;N-CoR;N-CoR1
Organism-1
Human
基因ID-1
9611
SwissProt-1
O75376
Organism-2
Mouse
SwissProt-2
Q60974
背景
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010],
细胞定位
Nucleus .
