- 产品信息
商品描述
靶点-Target
N-cadherin
反应性
Human,Mouse,Rat
应用
IHC,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
推荐稀释比
IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human N-cadherin expressed in E. Coli.
特异性
N-cadherin Monoclonal Antibody detects endogenous levels of N-cadherin protein.
基因名称
CDH2
蛋白名称
Cadherin-2
别名
CDH2;CDHN;NCAD;Cadherin-2;CDw325;Neural cadherin;N-cadherin;CD antigen CD325
Organism-1
Human
基因ID-1
1000
SwissProt-1
P19022
Organism-2
Mouse
基因ID-2
12558
SwissProt-2
P15116
Organism-3
Rat
基因ID-3
83501
SwissProt-3
Q9Z1Y3
背景
This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell membrane, sarcolemma . Cell junction . Cell surface . Colocalizes with TMEM65 at the intercalated disk in cardiomyocytes. Colocalizes with OBSCN at the intercalated disk and at sarcolemma in cardiomyocytes. .





