- 产品信息
商品描述
靶点-Target
NAC-1
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
57kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human NAC-1 expressed in E. Coli.
特异性
NAC-1 Monoclonal Antibody detects endogenous levels of NAC-1 protein.
基因名称
BTB14
蛋白名称
Nucleus accumbens-associated protein
别名
NACC1;BTBD14B;NAC1;Nucleus accumbens-associated protein 1;NAC-1;BTB/POZ domain-containing protein 14B
Organism-1
Human
基因ID-1
112939
SwissProt-1
Q96RE7
Organism-2
Mouse
SwissProt-2
Q7TSZ8
背景
This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Feb 2012],
细胞定位
Nucleus. Cytoplasm. Distribution in the cytoplasm is dependent on phosphorylation. .





