FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MuSK
反应性
Human
应用
IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
推荐稀释比
IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant extracellular fragment of human MuSK (aa24-209) fused with hIgGFc tag expressed in HEK293 cell line.
特异性
MuSK Monoclonal Antibody detects endogenous levels of MuSK protein.
基因名称
MUSK
蛋白名称
Muscle, skeletal receptor tyrosine-protein kinase
别名
MUSK;Muscle;skeletal receptor tyrosine-protein kinase;Muscle-specific tyrosine-protein kinase receptor;MuSK;Muscle-specific kinase receptor
Organism-1
Human
基因ID-1
4593
SwissProt-1
O15146
Organism-2
Mouse
SwissProt-2
Q61006
背景
This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.[provided by RefSeq, Oct 2009],
细胞定位
Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein . Colocalizes with acetylcholine receptors (AChR) to the postsynaptic cell membrane of the neuromuscular junction. .
