- 产品信息
商品描述
靶点-Target
MTHFR
反应性
Human,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
75kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human MTHFR expressed in E. Coli.
特异性
MTHFR Monoclonal Antibody detects endogenous levels of MTHFR protein.
基因名称
MTHFR
蛋白名称
Methylenetetrahydrofolate reductase
别名
MTHFR;Methylenetetrahydrofolate reductase
Organism-1
Human
基因ID-1
4524
SwissProt-1
P42898
Organism-2
Mouse
SwissProt-2
Q9WU20
背景
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009],
细胞定位
cytosol,synapse,





