FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MEK-6
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
37kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human MEK-6 expressed in E. Coli.
特异性
MEK-6 Monoclonal Antibody detects endogenous levels of MEK-6 protein.
基因名称
MAP2K6
蛋白名称
Dual specificity mitogen-activated protein kinase kinase 6
别名
MAP2K6;MEK6;MKK6;PRKMK6;SKK3;Dual specificity mitogen-activated protein kinase kinase 6;MAP kinase kinase 6;MAPKK 6;MAPK/ERK kinase 6;MEK 6;Stress-activated protein kinase kinase 3;SAPK kinase 3;SAPKK-3;SAPKK3
Organism-1
Human
基因ID-1
5608
SwissProt-1
P52564
Organism-2
Mouse
基因ID-2
26399
SwissProt-2
P70236
背景
This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Binds to microtubules.
