FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MAP3K2
反应性
Human
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
70kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human MEK Kinase-2 expressed in E. Coli.
特异性
MEK Kinase-2 Monoclonal Antibody detects endogenous levels of MEK Kinase-2 protein.
基因名称
MAP3K2
蛋白名称
Mitogen-activated protein kinase kinase kinase 2
别名
MAP3K2;MAPKKK2;MEKK2;Mitogen-activated protein kinase kinase kinase 2;MAPK/ERK kinase kinase 2;MEK kinase 2;MEKK 2
Organism-1
Human
基因ID-1
10746
SwissProt-1
Q9Y2U5
Organism-2
Mouse
SwissProt-2
Q61083
背景
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Upon EGF stimulation, translocates into the nucleus.
