FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
LysRS
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
68kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of LysRS(aa90-174) expressed in E. Coli.
特异性
LysRS Monoclonal Antibody detects endogenous levels of LysRS protein.
基因名称
KARS
蛋白名称
Lysyl-tRNA synthetase
别名
KARS;KIAA0070;Lysine--tRNA ligase;Lysyl-tRNA synthetase;LysRS
Organism-1
Human
基因ID-1
3735
SwissProt-1
Q15046
Organism-2
Mouse
SwissProt-2
Q99MN1
背景
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
[Isoform Cytoplasmic]: Cytoplasm, cytosol . Cytoplasm . Nucleus . Cell membrane ; Peripheral membrane protein . Secreted . Secretion is induced by TNF-alpha (PubMed:15851690). Cytosolic in quiescent mast cells. Translocates into the nucleus in response to mast cell activation by immunoglobulin E (PubMed:23159739). .; [Isoform Mitochondrial]: Mitochondrion .
