FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
LPP
反应性
Human,Mouse,Monkey,Hamster
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
66kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human LPP expressed in E. Coli.
特异性
LPP Monoclonal Antibody detects endogenous levels of LPP protein.
基因名称
LPP
蛋白名称
Lipoma-preferred partner
别名
LPP;Lipoma-preferred partner;LIM domain-containing preferred translocation partner in lipoma
Organism-1
Human
基因ID-1
4026
SwissProt-1
Q93052
Organism-2
Mouse
基因ID-2
210126
SwissProt-2
Q8BFW7
Organism-3
Rat
SwissProt-3
Q5XI07
背景
This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
细胞定位
Nucleus. Cytoplasm. Cell junction. Cell membrane. Found in the nucleus, in the cytoplasm and at cell adhesion sites. Shuttles between the cytoplasm and the nucleus. It has been found in sites of cell adhesion such as cell-to-cell contact and focal adhesion which are membrane attachment sites of cells to the extracellular matrix. Mainly nuclear when fused with HMGA2/HMGIC and KMT2A/MLL1.
