- 产品信息
商品描述
靶点-Target
LAL
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
45kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of LAL expressed in E. Coli.
特异性
LAL Monoclonal Antibody detects endogenous levels of LAL protein.
基因名称
LIPA
蛋白名称
Lysosomal acid lipase/cholesteryl ester hydrolase
别名
LIPA;Lysosomal acid lipase/cholesteryl ester hydrolase;Acid cholesteryl ester hydrolase;LAL;Cholesteryl esterase;Lipase A;Sterol esterase
Organism-1
Human
基因ID-1
3988
SwissProt-1
P38571
Organism-2
Mouse
SwissProt-2
Q9Z0M5
背景
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014],
细胞定位
Lysosome .





