FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
KLHL22
反应性
Human
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
72kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human KLHL22 expressed in E. Coli.
特异性
KLHL22 Monoclonal Antibody detects endogenous levels of KLHL22 protein.
基因名称
KLHL22
蛋白名称
Kelch-like protein 22
别名
KLHL22;Kelch-like protein 22
Organism-1
Human
基因ID-1
84861
SwissProt-1
Q53GT1
Organism-2
Mouse
SwissProt-2
Q99JN2
背景
similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,
细胞定位
Cytoplasm, cytosol . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Nucleus . Lysosome . Mainly cytoplasmic in prophase and prometaphase. Associates with the mitotic spindle as the cells reach chromosome bi-orientation. Localizes to the centrosomes shortly before cells enter anaphase After anaphase onset, predominantly associates with the polar microtubules connecting the 2 opposing centrosomes and gradually diffuses into the cytoplasm during telophase (PubMed:23455478). Localizes to the nucleus upon amino acid starvation (PubMed:29769719). Relocalizes to the cytosol and associates with lysosomes when amino acids are available (PubMed:29769719). .
