- 产品信息
商品描述
靶点-Target
KLHL13
反应性
Human
应用
WB,IHC,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
74kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human KLHL13 expressed in E. Coli.
特异性
KLHL13 Monoclonal Antibody detects endogenous levels of KLHL13 protein.
基因名称
KLHL13
蛋白名称
Kelch-like protein 13
别名
KLHL13;BKLHD2;KIAA1309;Kelch-like protein 13;BTB and kelch domain-containing protein 2
Organism-1
Human
基因ID-1
90293
SwissProt-1
Q9P2N7
Organism-2
Mouse
SwissProt-2
Q80TF4
背景
This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010],
细胞定位
midbody,Cul3-RING ubiquitin ligase complex,





