- 产品信息
商品描述
靶点-Target
JMJD2A
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
121kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human JMJD2A expressed in E. Coli.
特异性
JMJD2A Monoclonal Antibody detects endogenous levels of JMJD2A protein.
基因名称
KDM4A
蛋白名称
Lysine-specific demethylase 4A
别名
KDM4A;JHDM3A;JMJD2;JMJD2A;KIAA0677;Lysine-specific demethylase 4A;JmjC domain-containing histone demethylation protein 3A;Jumonji domain-containing protein 2A
Organism-1
Human
基因ID-1
9682
SwissProt-1
O75164
Organism-2
Mouse
SwissProt-2
Q8BW72
背景
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009],
细胞定位
Nucleus .





