- 产品信息
商品描述
靶点-Target
JAK3
反应性
Human,Mouse
应用
WB,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
125kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human JAK3 expressed in E. Coli.
特异性
JAK3 Monoclonal Antibody detects endogenous levels of JAK3 protein.
基因名称
JAK3
蛋白名称
Tyrosine-protein kinase JAK3
别名
JAK3;Tyrosine-protein kinase JAK3;Janus kinase 3;JAK-3;Leukocyte janus kinase;L-JAK
Organism-1
Human
基因ID-1
3718
SwissProt-1
P52333
Organism-2
Mouse
基因ID-2
16453
SwissProt-2
Q62137
背景
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],
细胞定位
Endomembrane system ; Peripheral membrane protein . Cytoplasm .





