- 产品信息
商品描述
靶点-Target
Islet-1
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
39kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Islet-1 expressed in E. Coli.
特异性
Islet-1 Monoclonal Antibody detects endogenous levels of Islet-1 protein.
基因名称
ISL1
蛋白名称
Insulin gene enhancer protein ISL-1
别名
ISL1;Insulin gene enhancer protein ISL-1;Islet-1
Organism-1
Human
基因ID-1
3670
SwissProt-1
P61371
Organism-2
Mouse
SwissProt-2
P61372
背景
This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus .





