FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IRAK-4
反应性
Human,Mouse,Monkey
应用
WB,IHC,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
52kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human IRAK-4 expressed in E. Coli.
特异性
IRAK-4 Monoclonal Antibody detects endogenous levels of IRAK-4 protein.
基因名称
IRAK4
蛋白名称
Interleukin-1 receptor-associated kinase 4
Organism-1
Human
基因ID-1
51135
SwissProt-1
Q8TDF7
背景
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],
细胞定位
extracellular space,intracellular,nucleus,cytoplasm,cytosol,plasma membrane,endosome membrane,
