- 产品信息
商品描述
靶点-Target
IL-2
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
18kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of IL-2 expressed in E. Coli.
特异性
IL-2 Monoclonal Antibody detects endogenous levels of IL-2 protein.
基因名称
IL2
蛋白名称
Interleukin-2
别名
IL2;Interleukin-2;IL-2;T-cell growth factor;TCGF;Aldesleukin
Organism-1
Human
基因ID-1
3558
SwissProt-1
P60568
Organism-2
Mouse
SwissProt-2
P04351
背景
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008],
细胞定位
Secreted.





