FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IL-10
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
21kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human IL-10 expressed in E. Coli.
特异性
IL-10 Monoclonal Antibody detects endogenous levels of IL-10 protein.
基因名称
IL10
蛋白名称
Interleukin-10
别名
IL10;Interleukin-10;IL-10;Cytokine synthesis inhibitory factor;CSIF
Organism-1
Human
基因ID-1
3586
SwissProt-1
P22301
Organism-2
Mouse
SwissProt-2
P18893
背景
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011],
细胞定位
Secreted.
