- 产品信息
商品描述
靶点-Target
IKKα
反应性
Human
应用
WB,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
85kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human IKKα expressed in E. Coli.
特异性
IKKα Monoclonal Antibody detects endogenous levels of IKKα protein.
基因名称
CHUK
蛋白名称
Inhibitor of nuclear factor kappa-B kinase subunit alpha
别名
CHUK;IKKA;TCF16;Inhibitor of nuclear factor kappa-B kinase subunit alpha;I-kappa-B kinase alpha;IKK-A;IKK-alpha;IkBKA;IkappaB kinase;Conserved helix-loop-helix ubiquitous kinase;I-kappa-B kinase 1;IKK1;Nuclear factor NF-kappa-B
Organism-1
Human
基因ID-1
1147
SwissProt-1
O15111
Organism-2
Mouse
SwissProt-2
Q60680
背景
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Nucleus . Shuttles between the cytoplasm and the nucleus.





