FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IGF-1R
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Observed)
pro:155kD,recetor beta:95kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of IGF-IR expressed in E. Coli.
特异性
IGF-IR Monoclonal Antibody detects endogenous levels of IGF-IR protein.
基因名称
IGF1R
蛋白名称
Insulin-like growth factor 1 receptor
别名
IGF1R;Insulin-like growth factor 1 receptor;Insulin-like growth factor I receptor;IGF-I receptor;CD antigen CD221
Organism-1
Human
基因ID-1
3480
SwissProt-1
P08069
Organism-2
Mouse
SwissProt-2
Q60751
背景
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],
细胞定位
Cell membrane ; Single-pass type I membrane protein .
