FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HXK I
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,Flow Cyt,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
102kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human HXK I expressed in E. Coli.
特异性
HXK I Monoclonal Antibody detects endogenous levels of HXK I protein.
基因名称
HK1
蛋白名称
Hexokinase-1
别名
HK1;Hexokinase-1;Brain form hexokinase;Hexokinase type I;HK I
Organism-1
Human
基因ID-1
3098
SwissProt-1
P19367
Organism-2
Mouse
SwissProt-2
P17710
Organism-3
Rat
基因ID-3
25058
SwissProt-3
P05708
背景
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. [provided by RefSeq, Apr 2016],
细胞定位
Mitochondrion outer membrane ; Peripheral membrane protein . Cytoplasm, cytosol . The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (Probable). Dissociates from the mitochondrial outer membrane following inhibition by N-acetyl-D-glucosamine, leading to relocation to the cytosol (PubMed:27374331). .
