FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HGK
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
142kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of HGK (aa400-500) expressed in E. Coli.
特异性
HGK Monoclonal Antibody detects endogenous levels of HGK protein.
基因名称
MAP4K4
蛋白名称
Mitogen-activated protein kinase kinase kinase kinase 4
别名
MAP4K4;HGK;KIAA0687;NIK;Mitogen-activated protein kinase kinase kinase kinase 4;HPK/GCK-like kinase HGK;MAPK/ERK kinase kinase kinase 4;MEK kinase kinase 4;MEKKK 4;Nck-interacting kinase
Organism-1
Human
基因ID-1
9448
SwissProt-1
O95819
Organism-2
Mouse
SwissProt-2
P97820
背景
mitogen-activated protein kinase kinase kinase kinase 4(MAP4K4) Homo sapiens The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm .
