FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HFE
反应性
Human
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
40kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human HFE expressed in E. Coli.
特异性
HFE Monoclonal Antibody detects endogenous levels of HFE protein.
基因名称
HFE
蛋白名称
Hereditary hemochromatosis protein
别名
HFE;HLAH;Hereditary hemochromatosis protein;HLA-H
Organism-1
Human
基因ID-1
3077
SwissProt-1
Q30201
Organism-2
Mouse
SwissProt-2
P70387
背景
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type I membrane protein .
