FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GRK 2
反应性
Human,Mouse,Rat,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
80kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human GRK 2 expressed in E. Coli.
特异性
GRK 2 Monoclonal Antibody detects endogenous levels of GRK 2 protein.
基因名称
ADRBK1
蛋白名称
Beta-adrenergic receptor kinase 1
别名
ADRBK1;BARK;BARK1;GRK2;Beta-adrenergic receptor kinase 1;Beta-ARK-1;G-protein coupled receptor kinase 2
Organism-1
Human
基因ID-1
156
SwissProt-1
P25098
Organism-2
Mouse
SwissProt-2
Q99MK8
Organism-3
Rat
基因ID-3
25238
SwissProt-3
P26817
背景
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Cell membrane . Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse .
