GluR-3 Monoclonal Antibody

活动价:

¥880.00

市场价:¥1280.00

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产品规格:
  • 50μL
货号:

FAB2600658

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商品描述
  • 靶点-Target

    GluR-3

  • 反应性

    Human

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Mouse

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    101kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    Affinity purification

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 克隆性

    Monoclonal

  • 免疫原

    Purified recombinant fragment of human GluR-3 expressed in E. Coli.

  • 特异性

    GluR-3 Monoclonal Antibody detects endogenous levels of GluR-3 protein.

  • 基因名称

    GRIA3

  • 蛋白名称

    Glutamate receptor 3

  • 别名

    GRIA3;GLUR3;GLURC;Glutamate receptor 3;GluR-3;AMPA-selective glutamate receptor 3;GluR-C;GluR-K3;Glutamate receptor ionotropic;AMPA 3;GluA3

  • Organism-1

    Human

  • 基因ID-1

    2892

  • SwissProt-1

    P42263

  • Organism-2

    Mouse

  • SwissProt-2

    Q9Z2W9

  • 背景

    Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Interaction with CNIH2 and CNIH3 promotes cell surface expression. .