- 产品信息
商品描述
靶点-Target
GluR-3
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
101kD
推荐稀释比
WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human GluR-3 expressed in E. Coli.
特异性
GluR-3 Monoclonal Antibody detects endogenous levels of GluR-3 protein.
基因名称
GRIA3
蛋白名称
Glutamate receptor 3
别名
GRIA3;GLUR3;GLURC;Glutamate receptor 3;GluR-3;AMPA-selective glutamate receptor 3;GluR-C;GluR-K3;Glutamate receptor ionotropic;AMPA 3;GluA3
Organism-1
Human
基因ID-1
2892
SwissProt-1
P42263
Organism-2
Mouse
SwissProt-2
Q9Z2W9
背景
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Interaction with CNIH2 and CNIH3 promotes cell surface expression. .





