- 产品信息
商品描述
靶点-Target
GDF-8
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
43kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of GDF-8 expressed in E. Coli.
特异性
GDF-8 Monoclonal Antibody detects endogenous levels of GDF-8 protein.
基因名称
MSTN
蛋白名称
Growth/differentiation factor 8
别名
MSTN;GDF8;Growth/differentiation factor 8;GDF-8;Myostatin
Organism-1
Human
基因ID-1
2660
SwissProt-1
O14793
Organism-2
Mouse
SwissProt-2
O08689
背景
myostatin(MSTN) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016],
细胞定位
Secreted .





