FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
GABP-α
反应性
Human,Mouse
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
51kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human GABP-α (aa120-190) expressed in E. Coli.
特异性
GABP-α Monoclonal Antibody detects endogenous levels of GABP-α protein.
基因名称
GABPA
蛋白名称
GA-binding protein alpha chain
别名
GABPA;E4TF1A;GA-binding protein alpha chain;GABP subunit alpha;Nuclear respiratory factor 2 subunit alpha;Transcription factor E4TF1-60
Organism-1
Human
基因ID-1
2551
SwissProt-1
Q06546
Organism-2
Mouse
基因ID-2
14390
SwissProt-2
Q00422
背景
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010],
细胞定位
Nucleus.
