FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FoxP2
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
80kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human FoxP2 expressed in E. Coli.
特异性
FoxP2 Monoclonal Antibody detects endogenous levels of FoxP2 protein.
基因名称
FOXP2
蛋白名称
Forkhead box protein P2
别名
FOXP2;CAGH44;TNRC10;Forkhead box protein P2;CAG repeat protein 44;Trinucleotide repeat-containing gene 10 protein
Organism-1
Human
基因ID-1
93986
SwissProt-1
O15409
Organism-2
Mouse
SwissProt-2
P58463
背景
This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isofor
细胞定位
Nucleus .
