FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Fibrinogen β
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
56kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human Fibrinogen β (aa30-300) expressed in E. Coli.
特异性
Fibrinogen β Monoclonal Antibody detects endogenous levels of Fibrinogen β protein.
基因名称
FGB
蛋白名称
Fibrinogen beta chain
别名
FGB;Fibrinogen beta chain
Organism-1
Human
基因ID-1
2244
SwissProt-1
P02675
Organism-2
Mouse
SwissProt-2
Q8K0E8
背景
The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014],
细胞定位
Secreted .
