- 产品信息
商品描述
靶点-Target
ESET
反应性
Human,Mouse,Monkey
应用
WB,IF,ELISA
宿主物种-Host Species
Mouse
修饰-Modification
Unmodified
MW(Calculated)
143kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
克隆性
Monoclonal
免疫原
Purified recombinant fragment of human ESET expressed in E. Coli.
特异性
ESET Monoclonal Antibody detects endogenous levels of ESET protein.
基因名称
SETDB1
蛋白名称
Histone-lysine N-methyltransferase SETDB1
别名
SETDB1;KIAA0067;KMT1E;Histone-lysine N-methyltransferase SETDB1;ERG-associated protein with SET domain;ESET;Histone H3-K9 methyltransferase 4;H3-K9-HMTase 4;Lysine N-methyltransferase 1E;SET domain bifurcated 1
Organism-1
Human
基因ID-1
9869
SwissProt-1
Q15047
Organism-2
Mouse
SwissProt-2
O88974
背景
SET domain bifurcated 1(SETDB1) Homo sapiens This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011],
细胞定位
Nucleus . Cytoplasm . Chromosome. Associated with non-pericentromeric regions of chromatin. Excluded from nucleoli and islands of condensed chromatin. .





